Diabetic nephropathy protein knowledge? How to reduce blood sugar?

Diabetic nephropathy protein knowledge? How to reduce blood sugar? Patients with this problem brings a great guide, end-stage diabetic nephropathy in patients only undergoing dialysis, there are two main ways: long-term hemodialysis and ambulatory ... Diabetic nephropathy urine protein high emergence of the reasons for the exclusion of high blood sugar, hypertension, urinary tract infection and kidney disease ... how to lower blood sugar for diabetic nephropathy urinary protein knowledge?? This problem can refer to the following:


High urinary protein in diabetic nephropathy knowledge of diabetic nephropathy urine protein high emergence of the reasons for the the substandard exclude the impact of hyperglycemia, hypertension, urinary tract infection and other kidney disease and heart failure, diabetic proteinuria was mainly due to the kidney glomerular basement membrane damage caused. Diabetic proteinuria is an important window to determine nephropathy or not.


Diabetic nephropathy urine protein high The reason is because due to chronic hyperglycemia. Some patients look through the surface of the drug control blood sugar better, but because drugs play a role at the same time, the body self-regulation mechanism disorder caused by high blood sugar remains in the event. Stimulation caused by high blood sugar on blood vessels still exist, the long run can lead to renal artery damage, chaos in the secretion of regulatory function, namely, the balance mechanism of the NO (vasodilator) and ET-1 and TXA2 (angiotensin factor) disrupted The increase in ET-1, of TXA2 synthesis, NO synthesis reduce the incidence of vascular microcirculation, leading to ischemia and hypoxia, and thus damage the small renal artery endothelial cells. Endothelial cells, once damaged, can cause renal inflammatory response leading to damage of the glomerular basement membrane, resulting in the leakage of the macromolecular protein, renal fibrosis starts.


Diabetic nephropathy in high urinary protein to become an important factor affecting the prognosis of diabetic nephropathy:


At present, high blood sugar, blood pressure, high cholesterol, proteinuria, high-protein diet, smoking, kidney disease family history and obesity and other risk factors of diabetic nephropathy has been recognized, including diabetic proteinuria sugar renal primary risk factors, diabetes nephropathy the protein high and the duration will greatly affect the prognosis.


Diabetic proteinuria is divided into three, microalbuminuria (urinary albumin excretion 3O ~ 300mg/24h), massive proteinuria (urine protein 0 3g ~ 3.0g/24h), heavy proteinuria (urine protein> 3. 0g/24h, often accompanied by hypoproteinemia and edema), three proteinuria is a gradual process, as long as the disease will continue to progress. Leakage accompanied by proteinuria, the disease will continue to increase, and thus give rise to edema, and hypoproteinemia.